How FRESHKOTE® Preservative Free (PF) works
FRESHKOTE PF offers patients nurturing relief from dry eye symptoms while reducing further irritation1,2
FRESHKOTE PF is a lubricant eye drop designed to support all layers of the tear film.1,2
The active ingredients in FRESHKOTE PF are a patented polymer blend with a unique ratio of polyvinyl alcohol and povidone1,2
MUCOAQUEOUS LAYER
Polyvinyl Alcohol (2.7%)1-3
- Mimics the mucin layer of the tear film by tightly adhering to dry hydrophobic spots, making them hydrophilic
- Attracts the aqueous portion of the tear film to these areas, completely wetting the ocular surface
LIPID LAYER
Povidone (2.0%)1,2
- Integrates with the lipid layer, supplementing it and thereby reducing evaporation while lubricating and soothing the ocular surface
HIGH ONCOTIC PRESSURE
Unique Ratio Blend1,2
- FRESHKOTE PF was scientifically developed to result in high oncotic pressure when on the ocular surface
High oncotic pressure draws excess water from epithelial cells4
References: 1. Holly FJ. Lacrophilic ophthalmic demulcents. US Ophthalmic Rev. 2007;3:38-41. 2. FRESHKOTE PF Drug Facts. Eyevance Pharmaceuticals LLC; 2018. 3. Willcox MDP, Argüeso P, Georgiev GA, et al. TFOS DEWS II tear film report. Ocul Surf. 2017;15(3):366-403. 4. Holly FJ. Colloidal Osmosis — Oncotic Pressure. Grapevine, TX: Dry Eye Institute; 2006. 5. Fuller DG, Connor CG. Safety and efficacy of FreshKote® used as a rewetting agent in Lotrafilcon-A® contact lens wearers. Poster presented at: American Academy of Optometry Annual Meeting; November 17-20, 2010; San Francisco, CA. 6. Nemera. Novelia®. https://nemera.net/products/ophthalmic-novelia-eyedropper/. Accessed March 14, 2019.
